Thursday, August 27, 2020

DESIGNING AND PREPARING TO IMPLEMENT AN EVALUATION Research Paper

Planning AND PREPARING TO IMPLEMENT AN EVALUATION - Research Paper Example Hence, there is have to assess the utilization of Vermont Immunization Registry and join it into a family clinical focus. Method of reasoning Center for Disease Control contends that the ongoing increment in vaccination of youngsters has prompted the expansion in maladies like Polio, Measles, and Pneumonia, in light of the fact that there is nothing but bad database that can record all the immunizations that a kid has been given. Thus, CDC concluded that Vermont Immunization Registry be assessed to decide its qualities and shortcomings. Vaccination has been recognized as a savvy and gainful methods through which new diseases are eradiated or diminished. This venture involves the formation of an automated framework through which vaccination records can be securely kept and kept up. It is consequently that the Vermont Immunization Registry (IMR) was actualized into the Family Medical Center. The library was to advance quality and productive treatment for the patients and to guarantee t hat all inoculations are done on schedule and legitimate records kept. As indicated by Centers for Disease Control and Prevention (2004) vaccination has prevailing with regards to killing sicknesses, for example, smallpox, measles, poliomyelitis, and rubella around the world (Meri, Jordens, and Jarva, 2008). An automated framework for keeping up records of vaccination is required. The framework should follow the inoculation dates, printed school, and parent reports. It is fundamental in directing and timing the proper time for organization of antibodies. Medicinal services suppliers for as long as two years have dissipated the clinical record papers. Guardians, in this way, end up searching for their inoculation records. This has helped in sparing numerous by guaranteeing that the correct immunization is controlled to the youngsters (Maciosek et al., 2006). Proclamation of the Problem Most of the guardians battle with inoculation strategies and dates. The exploration gives methods o f preparing guardians on the best way to get to their inoculation information through the PC whenever. The vast majority of the medical caretakers, specialists, and relatives are additionally confronting a test in using this program subsequently the requirement for assessment Purpose of Evaluation It is significant for wellbeing administrations, specialists, and patients to get to their immunization data whenever. This report shows the effectiveness and favorable circumstances of getting to this data. This examination will assess the viability of Solution Criteria To have the option to get to immunization information at wherever everywhere throughout the world Proposed Task Statement The issue can be fathomed by introducing a PC direct on the most proficient method to effectively enter the information. Designation of assets by the administration additionally should be modified. Partners Primary CDC-they are the reference point and guarantee they support completely the assessment pro gram. They are likewise answerable for the assessment program. Monetary Committee-The chief of money must guarantee assignment of assets for the assessment program for all the emergency clinics inside US. Optional Stakeholders Supervisors-Supervisors will be accountable for guaranteeing that there is legitimate preparing of the clinical staff and guarantee full interest of each one of those included. Volunteers Staff and Parents Volunteer’s staff and guardians will be liable for participating in the preparation program to guarantee there is full assessment of the Vermont Immunization Registry for what's to come. Tertiary Stakeholders Investors-this will incorporate the private and open financial specialists who are targeting providing the PC machines and overhaul programs. Key Evaluation Questions The assessment of this preparation program will mean to respond to the accompanying inquiries: 1. What do the volunteers, staff, chiefs, and upper level administration consider the current preparing program? 2. What are those that participate in the preparation learning because of

Saturday, August 22, 2020

The Resource Based View Analysis

The Resource Based View Analysis This report surveys observational investigations of the asset based view (RBV) and analyzes the advantages and restrictions of RBV as the best system course in the building up an organizations technique. By having a reasonable and centered key plan, it assembles an association towards accomplishing the longing position. Through breaking down its inner and outside condition utilizing the asset based view and Porters industry investigation separately, firm would have the option to accomplish supportable upper hand. The way in to an asset based view is through an understanding the connections between assets, abilities, upper hand, and monetary lease. The RBV distinguished qualities of preferred position making assets, for example, esteem, irregularity, imitability and Organization (Clulow et al, 2007; Barney, 1991). Interestingly, doormen industry investigation centers around lower cost and item separation in accomplishing maintainable upper hand. Regardless of the clashing issues, the asset based view has inspected issues and new bearings that will assist with explaining the worth and limits of the RBV by incorporating with Porters industry examination. Doormen system and the RBV of the firm fundamentally apparent the essential job of procedure as accomplishing a special upper hand (Hax A. C. also, Wilde II D. L., 2003). In this way, the two structures can supplement each other as they underscore in various elements of methodology (Hax A. C. furthermore, Wilde II D. L., 2003). (200 Words) Presentation The asset based perspective on the firm (RBV) is one of the contemporary vital administration ideas to build up an organizations system. The essential target of this report is to acknowledge or dismiss the dispute that asset based view investigation (RBV) has a solid relationship with firms execution in accomplishing a supportable upper hand. This report surveys the writing on upper hand and firm execution. It is isolated into five primary parts. The primary area sums up the writing on upper hand from two perspectives, the Resource Based View (RBV) and Porters Industry Analysis (IA). The subsequent area talks about on the qualities of the RBV in surveys with the writing on key expectation, edge assets, capacities, upper hand, center capabilities, economical upper hand and VRIO. The third segment shows Porters IA in surveys with cost, separation, and market center. The fourth segment ponders the reactions of the RBV and delineates how analysts have or have not conquered a portion of these limits. The fifth area is a survey of a combination of the RBV and Porters IA in the proposed model of center skills, upper hand and firm execution (Chabert J. M., 1998) (185 Words) The Resource Based View of the Firm Thompson et Al (2010) call attention to that RBVÂ [1]Â uses a companys VRIOÂ [2]Â strengths and serious abilities to convey an incentive to clients in way that adversaries think that its hard to coordinate. The RBV underlines the inner abilities of the association in figuring procedure to accomplish a SCAÂ [3]Â in its business sectors and ventures (Henry, 2008). It holds that organizations can win economical anomalous returns if and just they have predominant assets and those assets are secured by some type of detaching component forestalling their dispersion all through industry (Value Based Management.net, 2011). The Resourced Based View Assumptions The RBV of firms depends on two fundamental suspicions included asset assorted variety and asset idleness (Barney, 1991; Mata et al, 1995). As indicated by Mata et al. (1995), asset decent variety concerns whether various firms have groups of various assets and capacities; while asset idleness alludes to an asset is hard to get by contenders since it is inelastic in flexibly or exorbitant. These two presumptions can be utilized to decide if an association can make a SCA by giving a structure to deciding if a procedure or innovation gives a genuine favorable position over the commercial center (Brown, 2007). Therefore, the RBV will in general spotlight on the kinds of assets and the qualities of these assets that make them deliberately significant, the dynamic ability point of view which centers around how these assets need to change after some time to keep up their market importance (Powell, 2007). The RBV as the best procedure course in building up an organizations methodology Today administrators are moving assembling seaward to bring down expenses of work, supporting product offerings to catch worldwide scale economies, founding quality circles and without a moment to spare creation, and embracing Japanese human asset rehearses. It was accepted that the utilization of ideas like key fit (among assets and openings), conventional systems (minimal effort, separation and market center) and the methodology chain of command (objectives, methodologies, and strategies) have frequently helped the procedure of CAÂ [4]Â (Hamel and Prahalad 1989; Andrews, 1971). Most organizations have moved toward contender examination that centers around the current assets like human, specialized and money related of present contenders. While, the main danger those organizations mindful are those with the assets to disintegrate edges and piece of the overall industry later on. There are scarcely any Japanese organizations had RBV, fabricating volume or specialized fitness of U.S . what's more, European pioneers. For example, Canons initially stopping steps in reprographics business looked sadly little contrasted and the $4 billion Xerox powerhouse (Hamel and Prahalad 1989). Vital Intent Vital aim imagines an ideal initiative position and sets up the basis the association will use to graph its encouraging where Komatsu set out to circle Caterpillar. The idea underlines a functioning administration process that included concentrating the associations consideration on the embodiment of winning, spurring individuals by conveying the estimation of the objective, leaving spaces for individual and group commitments, continuing enthusiasms by giving new operational definitions as conditions change and utilizing expectation reliably to direct asset assignments (Hamel and Prahalad, 1989). Vital purpose catches the pith of winning. For instance, the Apollo program where handling a man on the moon in front of the Soviets was as seriously engaged as Komatsus drive against Caterpillar. It is steady after some time, so as to challenge worldwide authority; one of the most basic errands is to extend the associations capacity to focus. It gives consistency to transient activity, which leaving a space for reevaluation as new open doors rise (Hamel and Prahalad, 1989). A firm is said to have a CA when the firm can deliver all the more financially and higher consumer loyalty, and in this way appreciate better execution relative than its rivals (Barney, 1991; Peteraf, 1993). Though, Porter (1985) characterized CA as the capacity to acquire rates of profitability reliably over the normal for the business by concentrating on the companys outside serious condition and how they position themselves against that structure (Halawi L. An., Aronson J. E, and McCarthy R. V., 2005). Interestingly, the RBV of system focuses not to industry structure however to the remarkable bunch of RCÂ [5]Â that every association has (Henry, 2008; Collis and Montgomery 1995; Stalk et al, 1992). Firms Outperform and Maintain Competitive Advantage The Benefits of RBV RBV is best applied for the sort of evaluation of an organizations existing asset portfolio talked about by Barney (2001) or while misusing the organizations load of assets to move into new item advertises, as in the convention of Penrose (1959) (Sheehan and Foss, 2007). There are two crucial purposes behind creation the RC of the firm the establishment for its methodology. To start with, it gives the fundamental course to an organizations system and second, they are the essential wellspring of benefit for the firm. The RBV sees the worth got from the board aptitudes, data abilities, and managerial procedures can likewise be viewed as rare variables ready to create financial rents (Sheehan and Foss, 2007). The idea of a unique capacity was created to clarify why a few firms have had the option to outflank their rivals over extensive stretches of time and notwithstanding critical changes in the commercial center (Teece et al, 1997). Firms as heap of Resources Edge assets are characterized as the novel mix of benefits and abilities inside a firm that empower firms to create and execute procedures to meet clients least necessities and to improve its general execution (Scholes J. G., and Whittington, R., 2008). It very well may be named either unmistakable or impalpable assets. Substantial assets allude to the physical resources that a firm has and can be portrayed as physical assets. So as to include esteem, these physical assets must be skilled to react to commercial center changes. Impalpable assets include human and authoritative capitals. It might be implanted in schedules and practices that include created after some time inside the association (Henry, 2008). It incorporates information based economy, the unsaid information and master aptitudes of numerous workers which are hard for contenders to mirror (Henry, 2008). Nonaka and Takeuchi (1995) separate between information that can be viewed as unsaid and unequivocal. An express information or thinking about is appeared through correspondence that can be promptly moved in this manner it requires some type of security like copyright. Though, implied information or skill can't be classified and it is uncovered through its application and gained through practices, for example, convictions and viewpoints (Henry, 2008). RBV and Organizational learning The RBV stresses the criticalness of creating and upgrading those assets that are unmistakable, specifically, particular capacities (Olavarrieta and Ellinger, 1997). Ten

Friday, August 21, 2020

Writing Persuasive Essay Topics That Convert

Writing Persuasive Essay Topics That ConvertConviction is the crux of all persuasion. The aim of persuasive essay topics is to persuade the reader, as well as the audience, that you are a good, moral person. This leads to their acceptance of your position, or rejection of it.An unchangeable conviction can be the main reason for the acceptance of a persuasive essay topic. Conviction is exactly what you need if you want to convince others that what you are proposing is right. So, what is it?A conviction is an opinion, belief, attitude, or action that you hold about a good or bad cause. You hold it despite contradictory evidence and even contrary personal feelings about it. Conviction is not only about matters of the heart.Conviction is a subjective term. It relates to the quality of feeling, mood, emotion, or perspective about a person, idea, or situation. Conviction may involve such factors as personal values, political views, economic standing, common sense, personal orientation, or habit.As you might expect, you do not just 'have' a conviction, you do not hold it without the backing of your own convictions. Instead, it is the result of evaluating and weighing a number of different elements. When I use the term 'conviction' above, I am using it in a relative way, instead of identifying it as the same thing as acceptance.To become a persuasive writer, you must recognize and meet your own psychological needs, and those of the audience. In order to write persuasively, you must understand these needs and motivations. At the same time, you must also understand your reader's needs. Being well-versed in these two key areas will give you a clear advantage in convincing anyone to adopt your point of view.There are many methods of writing persuasive essay topics. One of the more conventional ones is to go back to the basics: to how you think. This is true because most people believe or accept what they hear or read simply because it sounds reasonable. Understanding the p sychology of people is critical to being a better persuasive writer.I have found the best ideas for criminal justice persuasion techniques from watching different talk shows and even reading some books. I don't think it matters if you watch television or read a book - you should always keep an open mind and explore as many different ideas as possible. If you take this approach, you will be a better persuasive essay topic writer.

Monday, May 25, 2020

Baking Ingredient Substitutions Table

Do you need to replace one ingredient with another in a recipe? Apply a bit of cooking chemistry to save your project.  This is a table of ingredient substitutions that you can make when baking. Changing the ingredient may affect the taste and texture of your recipe slightly, but this list should help prevent major differences. ammonium bicarbonate - 3/4 teaspoon1 tsp baking soda baking powder (single-acting) - 1 teaspoon1/4 teaspoon baking soda plus 1/2 teaspoon cream of tartar plus 1/4 teaspoon cornstarch baking powder (double-acting) - 1 teaspoon1/4 teaspoon baking soda plus 1/2 teaspoon cream of tartar plus 1/4 teaspoon cornstarch. Use 1 tsp for every 1 cup of flour. baking soda - 1/2 teaspoon2 teaspoons double-acting baking powder (replace the acidic liquid in recipe with non-acidic liquid) baking soda - 1/2 teaspoon1/2 teaspoon potassium bicarbonate buttermilk - 1 cup (240 ml)1 tablespoon lemon juice or vinegar plus enough milk to make 1 cup (240 ml) (let mixture stand 5-10 minutes)more buttermilk recipes cake flour - 1 cup (130 grams)3/4 cup (105 grams) all purpose flour plus 2 tablespoons (30 grams) cornstarch cake flour - 1/3 cup1/3 cup all-purpose flour less 1/2 teaspoon chocolate (bittersweet or semi-sweet) - 1 ounce (30 grams)1/2 ounce (15 grams) unsweetened chocolate plus 1 tablespoon (15 grams) granulated sugar chocolate (unsweetened) - 1 ounce (30 grams)3 tablespoons (20 grams) natural cocoa powder (not Dutch-processed) plus 1 tablespoon (14 grams) unsalted butter, shortening, or vegetable oil cocoa powder, Dutch-Processed - 3 tablespoons (20 grams)1 ounce (30 grams) unsweetened chocolate plus 1/8 teaspoon baking soda. Also reduce fat in recipe by 1 tablespoon. cocoa powder, natural unsweetened - 1 ounce (30 grams) unsweetened chocolate. Also reduce fat in recipe by 1 tablespoon. coffee, strong - 1/4 cup (60 ml)2 tablespoons (10 grams) instant coffee in 3 tablespoons hot water corn syrup, dark - 1 cup (240 ml)3/4 cup (180 ml) light corn syrup plus 1/4 cup (60 ml) light molasses corn syrup, light - 1 cup (240 ml)1 cup (200 grams) granulated white sugar (increase the liquid in the recipe by 1/4 cup or 60 ml) cornstarch (for thickening) - 1 tablespoon (15 grams)2 tablespoons (25 grams) all purpose flour cream of tartar - 1/2 teaspoon1/2 teaspoon white vinegar or lemon juice cream - half-and-half - 1 cup (240 ml)7/8 cup (210 ml) whole milk plus 2 tablespoons (25 grams) melted unsalted butter cream, heavy (not for whipping) - 1 cup (240 ml)2/3 cup (160 ml) whole milk plus 1/3 cup (75 grams) melted unsalted butter flour, self-rising - 1 cup (140 grams)1 cup (140 grams) all-purpose flour plus 1-1/2 teaspoons baking powder plus 1/4 teaspoon salt flour, whole wheat - 1 cup (150 grams)7/8 cup (120 grams) all-purpose flour plus 2 tablespoon (6 grams) wheat germ honey - 1 cup (240 ml)3/4 cup (180 ml) light or dark corn syrup plus 1/2 cup (100 grams) granulated sugar lard - 1/2 cup (113 grams)1/2 cup (113 grams) solid vegetable shortening lard - 1/2 cup (113 grams)1/2 cup (113 grams) plus 1 tablespoon (14 grams) unsalted butter marshmallow cream - 2.5 ounces8 large marshmallows or 1 cup miniature marshmallows milk (sweetened condensed) - 14 ounce can (396 grams)blend 1 cup instant nonfat dry milk plus 2/3 cup (135 grams) granulated sugar plus 3 tablespoons (35 grams) melted unsalted butter plus 1/2 cup (120 ml) boiling water milk (evaporated whole) - 1 cup (240 ml)1 cup (240 ml) half half milk (whole) - 1 cup (240 ml)1 cup (240 ml) skim milk plus 2 tablespoons (25 grams) melted butter or margarine molasses - 1 cup (240 ml)1 cup (240 ml) dark corn syrup sour cream - 1 cup (225 grams or 8 ounces)1 cup plain yogurt sour cream - 1 cup (225 grams or 8 ounces)1 tablespoon lemon juice or vinegar plus whole milk to fill 1 cup (240 ml) tapioca, instant or quick-cooking - 1 tablespoon (12 grams)1-1/2 tablespoons (20 grams) flour vinegar - 1/4 cup (60 ml)1/3 cup (80 ml) freshly squeezed lemon juice yogurt, plain - 1 cup (225 g)1 cup (225) sour cream

Thursday, May 14, 2020

The Risks In Finance And The Basel Guidelines Finance Essay - Free Essay Example

Sample details Pages: 11 Words: 3377 Downloads: 8 Date added: 2017/06/26 Category Finance Essay Type Research paper Did you like this example? What is finance? Finance is all about the knowledge of funds management. Simply speaking, to finance something is the same as to fund something. The funds can be in form of loans, bonds, owned capital, shares, etc (anything that can generate funds legally). So in finance, we learn anything that directly or indirectly related to funds management. Whether it is interest rate, time value of money, the calculation of risk, how to measure movement of share price, etc. All of these are related to finance. Direct Finance. Direct finance comprises of every direct transaction on the financial market, transaction with no middleman or agent. For example: Shareholders buy share to fund a company or buy government bonds to finance the government. Another example of direct finance is the internal capital market of multinational organizations. Semi direct Finance: The bank acts like an agent or intermediate party. In return, they receive fee/commission for the transaction. Banks dont take position in the transaction; they strictly serve as a middleman and therefore are free from the risks that the transaction bears. Don’t waste time! Our writers will create an original "The Risks In Finance And The Basel Guidelines Finance Essay" essay for you Create order Indirect Finance In indirect finance, which most people referred to as banking, banks take the direction/initiatives of all of activities. For example they receive money from households and lend it to organizations. Its not the household decision anymore how to use the money (for financing purpose); therefore we call it indirect. For example: Households save their deposit into bank in return of interest and the bank decide to loan the money to others (person, organization, company, etc) at higher interest rate (the difference becomes the banks profit). That way the bank will make a profit. In other case, the bank can choose to enter the stock market or buying bonds of its own choosing, etc in order to generate profit. This is the basic of banking. Many different kinds of risks exposed to the bank. Banks are exposed to many risks such as: Liquidity risk. Liquidity risk means that a given asset cant be sold quickly enough in the market to avoid a loss. This is the case when illiquid assets have to be sold in a short term. This is similar with cash flow insolvency. For example: Properties (hard to sell without incurring a loss at a short period of time). Liquidity risk can also mean that a bank isnt capable of paying her debts at a short term (similar to cash flow insolvency). This is different with balance sheet insolvency (negative net assets, therefore unable to pay). A bank maybe balance sheet solvent but still exposed to liquidity risk if it holds lots of illiquid assets. For example: Northern Rock (a perfect example of bank run). A bank run happens when large number of bank customers withdraw their deposits at the same period of time because of the fear the bank is unable to pay. In Northern Rock case, when the global demand for securitised mortgages droppe d in August 2007, Northern Rock became unable to pay back the loans from the money market with money which should have been raised from securitisation. On 14 September 2007, the bank obtained a liquidity support facility from the Bank of England, to return the funds it was unable to get from the money market. The banks assets were enough to cover its liabilities, but it suffered from liquidity problem. Because of this news, Northern Rock suffered a bank run and needed government intervention to guarantee its customers money. Later on, Northern Rock is nationalized. Credit risk/ counterparty risk/ default risk. It can be defined as any loss in the market value due to different reasons. It means as an investors risk of loss arising from a borrower who fails to make payments as promised. Or, it can also mean the loss because of the difference in firm value/ company value because the bank credit rating (one of the example) collapsed due to something happening within the bank (borr ower fails to pay up, bad management, etc)/ indirectly related to the bank. Market risk. Market risk is the risk that the value of a portfolio, going to decrease because of the change in value of the market risk factors. In case this happens, the bank will occur a loss. The four main factors are stock prices, interest rates, foreign exchange rates, and commodity prices. Therere 4 different kinds of market risk, such as: Equity risk, the risk that stock prices will change. Foreign exchange rate risk, the risk that foreign exchange rates will change. Interest rate risk, the risk that interest rates will change. Commodity prices, the risk that commodity prices will change. Operational risk. Operational risk is the failure of the people of the procedures of the systems. For example the mistyped case (fat finger) or simply known as typo. Example: Buying shares for $500, but instead mistypes it once so it becomes $5000. One of the biggest examples of operatio nal risk is Barings Bank, collapsed in 1995 after its employees, Nick Leeson, lost $1.3 billion speculating primarily on futures contracts and subsequently lost it all. Leeson was able to operate with no supervision from head office because of the banks poor internal auditing and risk management practices. Another type of operational risk is legal risk. In order to operate, the bank must operate based on the government rules and regulation. This is how the legal risk arises. It is a risk that arises when the bank is not in compliance with government regulation and therefore hinders it to enter a transaction or to operate. It includes the time and money wasted for the legal proceedings (or as a result of it, such as opportunity lost, etc) that the bank must endure in case it is accused of illegal conduct (or vice versa). It is one of the greatest challenges for managers to make their bank in compliance with government regulation. It is very difficult to predict the size of legal r isk. Its also very bad for the banks reputation. Settlement risk Settlement risk can be described as the risk that a counterparty fails to deliver a security or its value in cash per agreement when the security was traded after the other counterparty have already delivered security or cash value per the trade agreement. For example: Foreign exchange settlement risk or simply known as Herstatt risk. On 26th June 1974, some banks had undertaken foreign exchange transactions with Herstatt and had already paid Deutsche Mark to the bank during the day, believing they would receive US dollars later the same day in the US from Herstatts US nostro. But at the end of banking day, Herstatts topped all dollar payments to counterparties. As a result, the banks license was withdrawn because of a shortage of income and capital to make up for liabilities that were due. Reputational risk. Reputational risk is a type of risk related to the reliability of company. It may result in lost revenue or damage to shareholder value, ignoring to the fact whether the bank is actually guilty or not. Its about the image of the bank. Therefore, its related to many risks. If the bank is unable to settle its transaction (transaction risk) or have bad operation (operation risk) or making a big loss in financial market because of market risk, they all can damage the banks reputation, etc. Any kind of actions, wrongdoings, news that can have negative impact to the bank (whether its directly or indirectly (such as counterparties or investors bad reputation) related to the bank) can be considered as reputational risk. Therefore, reputational risk is closely related to the other risk. Other risks. There are many other risks that are exposed to the bank but havent been described in the lecture yet, such as systemic risk (risk of the collapse of entire financial system/entire market. Example: Lehman brothers (almost happening)), profit risk, and volatility risk (the risk that ari ses because the likelihood of fluctuations in the exchange rate of currencies). Saving mechanisms. Lender of last resort. Lender of last resort, as the name speaks for itself, is an organization which is willing to lend money to a bank when theres no alternative left. Usually banks want to avoid doing this, because it is damaging to the banks reputation and shows that the bank is in some sort of trouble (like what happen to Northern Rock, once they asked the Bank of England to bail them out, they suffered a bank rush). Most of the time, lender of last resort is the central bank of the country. Deposit insurance system. Every bank has to put a small percentage/portion of every deposit that its customers made in an insurance pool that is used to back up the customers deposit. This is useful when a bank has some liquidity problems, customers dont need to be a scared to lose all their money. But put in mind that the portion is relatively small. Maybe it can cover small banks, but not the big one. Capital adequacy. Banks are obliged to have minimum capital requirements to prevent them from failing. The more capital they have, the safer they are to meet their financial demands and obligations (because capital is their own money and they can use it for their own needs and demands). Bad banks. Bad bank is a term for financial institution that are created to keep the nonperforming assets owned by a state guaranteed bank. Bad banks are legal institutions that are used to isolate toxic products in order to save the healthy part of the bank. It is sometimes used to save the majority of the banks. Intentionally lose the bank in order to keep the others safe and afloat. Government bailout. Sometimes the government put themselves in, bailing the bank, financial institution, etc, in order to save the financial market (or in bigger case, the nations economy itself) from crisis and prevent it from systemic risk / collapsing. Capital Adequacy (Lecture 2). Basel I: Basel I is discussions by central bankers around the world in the year 1988 and resulted in a set of guideliness about minimal capital requirements for banks in case they want to lend their money . It was used by the G-10 countries before a more advanced guideliness made (notably Basel II). How Basel I works? Basel I implies that every time a bank makes a loan to other institution (then in balance sheet of the bank it is put on debit side by nature), the bank needs to have certain amount of equity on its credit side as a backup in case the loan gone bad. Example: If you give loan for $100 and put $100 on your asset side (left side of balance sheet), youll need to have 8 (as example) as equity on the liability side (right side of balance sheet. This 8 is different for different type of assets. Lending to government is much safer than lending money to corporation. How to differentiate it? We use risk weight. Example: If the lender is government, we use risk weight of 0% ( we assume the government is perfectly safe). For bank we use a risk weight of 20%. For mortgage loan we use a risk weight of 50%. For company, which is the riskiest of them all, we use full weight (100%) to calculate the equity needed to backup the loan. Bottom line is the bank differ the equity needed to cover up the loan based on whos borrowing it (government being the safest and therefore have 0% risk weight, company being the most risky and therefore have 100% risk weight. And therefore we have the risk weighted assets of banks. Calculated as the different types of assets that bank has, multiply by the risk rate, then multiply by the predetermined equity that needs to be keep (in this case $8 for every $100 of loan). Example: Loan of $100 to government (asset side), then, equity needed = $8 X 0% = $0 (liability side). Loan of $100 to company, then, equity needed = $8 X 100% = $8 and so on. Amendment 1996: Capital has to be set aside for Market Risk. In Basel I there was no rule for modeling. The only thing we did was classifying. Bank need to look this amendment and make a benchmark model for its own use. Translate it into percentage of returns. Create a histogram and cut off the tail (1% probability mass). The position of cut off tail is the value at risk (VAR). It determines which position is accepted and which one is below standard and therefore imposed to extra charge. It is a quantile of distribution. It is the base on which the capital set aside for market risk is calculated. Now bank has to model the changes in the value of the portfolio of the company/ borrower. If a company exceeds this VAR (loss is bigger than VAR) by 1%, then the company performs well. If it exceeds 1%, then company will receive an extra capital charge. Usually the multiplier is 3 (can be more). Bank has to present this model to the regulator. Basel II Basel II is an improved second version of Basel I. Basel II had undergone many proposal and updates as well as received much response. Quantitative impact studies ƒ   banks implement Basel II on a trial basis to check if it has an impact on their capital etc. There are 3 main point need to be stressed out on Basel II, such as: First pillar: Capital adequacy. Basel II still keeps the 1996 amendment with respect to market risk. Banks still have to keep capital aside for credit risk. Credit risk can be calculated in 3 ways component can be calculated in three different ways, such standardized approach, foundation IRB and advanced IRB. In standardized approach, risk weights are different for each individual borrower in each group. So now there is a credit rating (which is generated by external parties) which is different for each category. Lending to blue-chip company is absolutely safer than lending money to small unknown company. This is what Basel I lacks . The borrower is regrouped 2 times, therefore it is more accurate (we simply multiply the equity needed one more time based on the borrower rating which holds different rate of multiplier). Alternatively, bank can use Internal Rating-Based approach (banks are allowed to model the default probabilities of their own customers) was proposed. Second pillar: supervisory review. All banks have to model their economic capital and regulatory capital (the capital that the bank has to maintain in compliance with the law). Moreover, banks operate on the economic capital (their working condition), which (usually) is above the legal minimum. It gives the regulators much improved instruments compared to Basel I and framework to deal with the risk that a bank may face such as reputational risk, systemic risk, etc. It gives bank the ability to examine its own risk management system. Third pillar: market discipline, which means accounting disclosure. The idea is that we can safeguard banks if we let them disclose the riskiness of their positions. Bank needs to have a system in place to at least produce these numbers. By opening up their position, banks will be more thoughtful and careful in their actions. And regulator can keep track of them as well. 2.1. Financial market products. There are a lot of financial products; all has its own characteristic and classification. Examples of financial products are: Shares equity: : Certificates that represent that an investor has already invested in some form of investments (in the form of a company, etc) and therefore he/ she owns a portion of that investment and any underlying asset beneath it and entitled to claim any gains from that investment. Bonds: Certificates that represent money a government or corporation has borrowed from other entities. T-bills (Treasury Bills): Short term debt obligation guaranteed by the US Government with maturity of less than a year. Options: A contract that provides the buyer with the right to buy or to sell an underlying asset at a specific price during a specified time period. Futures: Contract between 2 parties to buy/ sell a standardized asset at specified future date with the price agreed today. Forwards: Same as futures with the exception that they are not exc hange-traded or standardized. Swaps: Agreement between parties to swap the benefits of their financial instrument. For example: In bonds, both parties agree to swap the coupon payments related with the bonds. Both coupon payments can have different payment timing and value. Commodities: Sold in commodity market where primary/ raw products are exchanged. Can be in form of derivatives trading or direct physical trading. Commercial paper: Corporations short term debt instrument (1 to 270 days), usually used for  the  funding of accounts receivable,  inventories or to  meet short-term liabilities. Strips (Separate Trading of Registered Interest and Principal Securities), as the name speaks for itself, strips is a seperate trading for the interest / principal portion for the securities. It is cut into different pieces which are sold separately. By this, strips can also give buyer a tax advantage (typical in Belgium). Medium term notes: A debt note that matures in 5 -10 years (usually). Foreign Exchange (Forex): Over the counter financial market for trading currencies. Forex have been known to use spot transaction regularly. In contrast with derivatives, the buyer buy right now, pay within 2-3 days time and you get instruments at that same period as well. Life insurance: Contract between the policy owner and insurer that the insurer will pay a sum of money to the owner in case of events (death, critical illness, etc). In relation to finance market, life insurance policy is so often combined with investment (get insured and have investment, managed by the insurer), with the exception of pure protection life insurance. Asset Backed Securities: A security whose value and payments determined by a specifically designed pool of underlying asset, usually illiquid assets. Doing so will allowed the asset to be sold into the financial market, therefore comes the term securitization (making securities from illiquid asset). Mortgage Backed Secu rities: The same as Asset Backed Securities, instead the cash flows now comes mortgage loans (underlying asset). Convertible bonds: A bond that can be converted to common stock shares at equal value by the issuing company. Repo (repurchase agreement): Agreement that lets the seller to buy back the securities from the buyer at a later date (usually a short one). 70% of repos mature in less than 7 days. Interbank loan: Direct loans between two banks to cover up their financial needs using predetermined interest rates (LIBOR Rates, etc). Credit Default Swap: Swap contract between buyer and seller with the buyer pays a series of payments to sell as an exchange of payoff in case a credit event happens to a credit instrument that currently being swapped. As the name speaks for itself, it swaps the default risk from one party to another in turns of payment. Mutual funds: Collective investment funds, gathered from numerous amount of people, institution and company and is mana ged by a professional fund manager, usually a bank, insurance company or investment company (and therefore the manager collects commission from it). The fund manager then can decide where to invest the fund in the financial market and therefore forming a portfolio. They also have different taxing implication than others. These financial products can be classified into many types (highlighted with different color), such as: Derivative (green color) is a financial tool, an agreement between 2 parties to transact something else (underlying asset). Therefore, derivatives value is determined by its underlying asset. Example: Option to buy AA shares for $20. If share AA goes up to $30, the option is worth $10. If share AA goes $20 or below, the option worth nothing. Thats option it is dependent to the value of its underlying asset. Its a type of linear products that gives you win-lose situation when bought and have a timeframe in it for it to do some effect (to gain or to lose). Money market (yellow color) and Capital Market (blue color). The main difference between money market and capital market is in the time to maturity / time frame. Money market being relatively short term (less than 1 year) and capital market being relatively long term (more than 1 year). The rest of the products such as commodities and Forex are slightly different and therefore have their own categories. Thats all about the summary of first and second lecture of CAF. We hope you find it useful.

Wednesday, May 6, 2020

Home Assignment on Whole Foods Market - 3430 Words

Home assignment on Whole Foods Market 1. Related products Whole Foods Market only sells products that meet its self-created quality standards for being natural, which the store defines as: minimally processed foods that are free of hydrogenated fats as well as artificial flavors, colors, sweeteners, preservatives and products that are listed on their online Unacceptable Food Ingredients list. Whole Foods Market has also announced that it does not intend to sell meat or milk from cloned animals or their offspring, even though the U.S. Food and Drug Administration (FDA) has ruled them safe to eat. The company also sells many USDA-certified organic foods and products that aim to be environmentally friendly and ecologically†¦show more content†¦They support what their consumers do. And then there is the political segment, which is the â€Å"†¦arena in which organizations and interest groups compete for attention, resources, and a voice in overseeing the body of laws and regulations guiding the interactions among nations† (H itt). This segment is very important to Whole Foods, as well as any other organic food retailer. It is important because all products have to pass FDA approval, if not then there goes waste of time and money. Whole Foods Market has been able to understand this segment, and by doing so has created their own policies when processing foods. This action not only adds creditability, but also assures that government regulations will be followed thoroughly. 3. In which industry does WFM compete and what are the dominant characteristics of this industry? The organic and natural food industry is a relatively large and popular one that continues to grow with every passing day. In the organic industry the â€Å"†¦range of competitors include chain and independent supermarkets; mass merchandisers and super centers; convenience stores; wholesale clubs; restaurants and fast food chains; natural food stores; local farmers’ markets, and internet grocers† (Lytel). Global growth of organic agriculture has gained much popularity, which continues to accumulate attention. The reason for that is simple, it is because this industry†¦ â€Å"†¦can be a profitable, sustainable business for those producers interested inShow MoreRelatedComparing Whole Foods and Trader Joe’s1345 Words   |  6 PagesComparing Whole Foods and Trader Joe’s For our case assignment, we decided to compare two grocery stores popular in the NYC area: Whole Foods and Trader Joe’s. 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When I looked up my neighborhood though it did show Livermore, a city that is about a five or less minute drive from me having a few low income spotsRead MoreMission Statement Analysis1128 Words   |  5 PagesMission Statement and Code of Ethics For this assignment I choose to look at two companies I am currently working for. I have been with these companies for a few years and I have worked in different positions within the companies. I feel I have a sense of how they are managed and can compare my experiences with them to their goals of the mission statements and code of ethics. The Home Depot Mission Statement The first company is The Home Depot. After reading the mission statement I feel thatRead MoreThe Company Whole Foods Market1560 Words   |  7 Pagesindividual assignment, I chose the company Whole Foods Market (WFM) which deals in selling products that are organic and fresh to its customers. WFM was founded by John Mackey and Renee Lawson Hardy, owners of Safer Way Natural Foods, and Craig Weller and Mark Skiles, owners of Clarksville Natural Grocery in Austin, Texas where the original store opened in 1980 and consisted of a staff of only 19 people. WFM was founded because those four local businesspeople decided the natural foods industry wasRead MoreManagement Of International Mobility1352 Words   |  6 PagesThis model identifies that management of international mobility entails the need to take a holistic approach to all aspects of the assignment process. (Sparrow, Brewster and Harris, 2004) However, although the model has its advantages in terms of pre-assignment preparatio n, some of the stages however do bring about some complexities for IM managers as outlined for by (Sparrow, Brewster and Harris, 2004) Selection- the need for precise recruitment and selection is needed; IM managers need to payRead MoreMarketing Case Study on Starbucks Coffee Essay1035 Words   |  5 PagesGalVal Instructor: Mr Tom Wall Section #: _25___ Assignment #2: Actual Case Study - Starbucks Coffee 1. The main or primary product that Starbucks sells or distributes is coffee beverages but, according to this article or company analysis, it also now offers a whole line of complementary products - from sandwiches to CDs! Yet essentially, Starbucks product was the de- velopment of the ultimate, out of home (OOH) coffee-drinking experience; also referred to as theRead MoreA Report On The Restaurant Group Plc1742 Words   |  7 PagesCoventry University – London Campus M002LON Sustainable Strategy Assignment: Formative Assessment Name: Nguyen Thi Ngoc Quynh Student ID: 5963386 Tutor: Jon Kitto Submission date: Word count: Executive Summary: Introduction: The Restaurant Group plc (â€Å"TRG† or â€Å"the Group†) is the leading British chain of restaurant, which were originally founded in 1987 with the establishment of Garfunkel’s chain of restaurants. During the period of time from 1987 to 2014, the Group operates overRead MoreNew Product Development1020 Words   |  5 Pagesbusiness in the country. For the last decade, the frozen pizza market was growing the fastest within the entire US frozen food industry, reporting at a rate of 29,2% between 1995 and 2000. This was caused by the introduction of the ‘rising crust’ technology, through which frozen pizza got almost the quality of the pizza offered in restaurants. This had a declining effect on the other three segments of the pizza branch (dine-in, take away and home delivery), because now having almost the same quality, frozenRead MoreMcdonald s, Burger King And Wendy s I Started1302 Words   |  6 PagesIndividual Assignment #1 Comparing McDonald’s, Burger King and Wendy’s I started to see some interesting aspects to their marketing strategies. First by focusing on their main economic characteristics, secondly looking more in depth at the competition and driving forces, and lastly their key success factors. They have been striving to make changes to increase market shares as well as trying to dominate a global fast food industry by competing in the products, places, prices, and promotions they offerRead MoreField Assignment1404 Words   |  6 PagesOlivia Gorena MRKT 1001- Field Assignment #1 1. (a) Find mission statements for three of your favorite companies or consumer brands. Explain how the mission statement for each gives a strategic direction. Explore the strengths and weaknesses of each and make recommendations how these can be streamlined to give better understanding. (b) Create a mission statement for your own career. Explain how this will help you in the job market. 1. Favorite Companies/ Brands i. Tofurky

Tuesday, May 5, 2020

International Law for Contract for International Sale of Good

Question: Discuss about theInternational Law for Contract for International Sale of Good. Answer: The United Nation Convention on Contract for International Sale of Goods is an international Treaty which has been ratified by 89 States. The treaty had been entered up on into for the purpose of establishing uniform International sales law. This treaty is also often referred to as the Vienna Convention. The primary purpose of the Treaty is to make arrangements for exporters in order to help them avoid issues in relation to choice of law. Through this treaty accepted substantial rules are provided which may be relied upon by the courts, arbitrators and contracting parties to resolve contractual issues. Where an Express term of a contract does not prohibit the incorporation of the Treaty it is deemed to be present in relation to contract between parties belonging to the member states of the Treaty. The application of the Treaty is done in relation to contract for sale of goods between those parties who operate in different states and the states are contracting states. The provisions o f the Treaty is also applicable in situation where one of the parties to the contract belong to a non contracting state and the conflict of law rules provides that the law of the contracting state would be applicable. The application of the Treaty is done in relation to Commercial products and goods only. In the light of certain exceptions the application of the Treaty cannot be done in relation to household, family or personal goods along with aircrafts, ships and intangible services. The parties to the contract have the right of excluding the incorporation of the Treaty into the contract. The Treaty is considered to be as the backbone of all countries international trade. Identified issue In the given situation the contract which has taken place between BigMi and the seller is between the contracting states of the convention. This is because the BigMi Company belongs to China who is a member of the convention and the seller belongs to the United States of America who is also a member of the convention. Thus as both the states from where the parties to the contract belong to the contracting states the provisions of CISG would be applicable. The issue which has been identified in the given situation is that the seller was supposed to receive a letter of credit as soon as the ship with the goods had been dispatched however BigMi has failed to provide the letter of credit to the seller as they were able to procure the goods at a less price. In the given situation the seller has been subjected to losses as it had to sell the goods at a lesser price and also include the cost of the charter. It has been provided through article 9 of the convention that any terms which have b een agreed by the parties between themselves are binding upon them. Therefore in the given situation as the letter of credit had not been provided to the seller when the goods were dispatched by the seller, BigMi have breached the contract with the seller. The primary issue is thus the breach of contract. In the given it has been provided that the contract which has been formed between Big Mi and the seller have same states party. This is because both New York as well as California belongs to a single state, which is the United States of America. It has been provided through the provisions of Article 1 of the CISG that the provisions of the convention would only be applicable where the parties belong to different states. Thus the as per the first interpretation the parties would not be applied with CISG as they belong to the other states. On the other hand it has been provided through the case study that the parent company of Big Mi is in China. In situation where the subsidiary company is liable a claim is made from the parent company. In the given situation where the contract had been breached as per Article 9 and 25 of the convention by the subsidiary company in New York the parent company would be liable. If this interpretation is taken then the application of article 1 in this situation can be done. It has been provided through the provisions of Article 1 of the CISG that the provisions of the convention would only be applicable where the parties belong to different states. Here China and USA are different states and the parties to the CISG. Thus the CISG would be applicable. References The United Nation Convention on Contract for International Sale of Good

Tuesday, April 7, 2020

Absorption Costing free essay sample

Absorption costing: * It is costing system which treats all manufacturing costs including both the fixed and variable costs as product costs * In absorption costing, all costs are absorbed into production and thus operating statements do not distinguish between fixed and variable costs. * Absorption costing is a process of tracing the variable costs of production and the fixed costs of production to the product. Absorption costing is used to cost products and to report financial performance. The cost of a product is made up of those direct costs that can be related directly to making it. For example the direct cost of a chair might be: 10 metres of wood at ? 6. 00 per metre 1 piece of moulded plastic 20 screws and washers 30 minutes of time Marginal costing: * It is a costing system which treats only the variable manufacturing costs as product costs. The fixed manufacturing overheads are regarded as period cost * In marginal costing, fixed production costs are treated as period cost and are written off as they are incurred The difference between marginal costing amp; absorption costing is as below: 1. We will write a custom essay sample on Absorption Costing or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Under marginal costing: for product costing amp; inventory valuation, only variable cost is considered whereas, Under absorption costing; for product costing amp; inventory valuation, both fixed cost amp; variable cost are considered. 2. Under marginal costing, there is a different treatment of fixed overhead. Fixed cost is considered as period cost amp; by Profit/Volume ratio (P/V ratio), profitability of different products is judged. On the other hand, under absorption costing system, the fixed cost is charged to cost of production. A reasonable share of fixed cost is to be borne by each product amp; thereby subjective apportionment of fixed overheads influences the profitability of product. 3. Under marginal costing, the presentation of data is so oriented that total contribution amp; contribution from each product gets highlighted. Under absorption costing, the presentation of cost data is on conventional pattern. After deducting fixed overhead, the net profit of each product is determined. 4. Under marginal costing, the unit cost of production does not get affected by the difference in the magnitude of opening stock amp; closing stock. Whereas, under absorption costing, due to the impact of the related fixed overheads, the unit cost of production get affected by the difference in the magnitude of opening stock amp; closing stock Financial Accounting Financial accounting is used to present the financial health of an organization to its external stakeholders. Board of directors, stockholders, financial institutions and other investors are the audience for financial accounting reports. Financial accounting presents a specific period of time in the past and enables the audience to see how the company has performed. Financial accounting reports must be filed on an annual basis, and for publically traded companies, the annual report must be made part of the public record. Management Accounting Management or managerial accounting is used by managers to make decisions concerning the day-to-day operations of a business. It is based not on past performance, but on current and future trends, which does not allow for exact numbers. Because managers often have to make operation decisions in a short period of time in a fluctuating environment, management accounting relies heavily on forecasting of markets and trends. Differences Management accounting is presented internally, whereas financial accounting is meant for external stakeholders. Although  financial management  is of great importance to current and potential investors, management accounting is necessary for managers to make current and future financial decisions. Financial accounting is precise and must adhere to Generally Accepted Accounting Principles (GAAP), but management accounting is often more of a guess or estimate, since most managers do not have time for exact numbers when a decision needs to be made. Management Accounting (MA) deals with non financial and a bit financial accounting. MA is very internal and it looks at the costs of production, how costs should be allocated, using labour hours, what costing method should we use, activity based costing or full cost costing. Financial accounting (FA) looks at financial information only. Like profit, sales, gross profit, and cost of sales. FA has accounting standards to follow like the  Accounting Standards (IAS). Whilst the MA can be presented in any form. FA is usually to communicate to the External Stakeholders (Govt, Owners, Customer, Banks etc.. ) and MA is usually for Internal Stakeholders (Employees, Managers, CEOs) Financial Accounts| Management Accounts| Financial accounts describe the performance of a business over a specific period and the state of affairs at the end of that period. The specific period is often referred to as the Trading Period and is usually one year long. The period-end date as the Balance Sheet Date| Management accounts are used to help management record, plan and control the activities of a business and to assist in the decision-making process. They can be prepared for any period (for example, many retailers prepare daily management information on sales, margins and stock levels). Companies that are incorporated under the Companies Act 1989 are required by law to prepare and publish financial accounts. The level of detail required in these accounts reflects the size of the business with smaller companies being required to prepare only brief accounts. | There is no legal requirement to prepare management accounts, although few (if any) well-run businesses can survive with out them. | The format of published financial accounts is determined by several different regulatory elements: ·Ã‚  Ã‚   Company Law ·Ã‚  Ã‚   Accounting Standards ·Ã‚  Ã‚   Stock Exchange| There is no pre-determined format for management accounts. They can be as detailed or brief as management wish. | Financial accounts concentrate on the business as a whole rather than analysing the component parts of the business. For example, sales are aggregated to provide a figure for total sales rather than publish a detailed analysis of sales by product, market etc. | Management accounts can focus on specific areas of a business activities. For example, they can provide insights into performance of: ·Ã‚  Ã‚   Products ·Ã‚  Ã‚   Separate business locations (e. g. hops) ·Ã‚  Ã‚   Departments / divisions| Most financial accounting information is of a monetary nature| Management accounts usually include a wide variety of non-financial information. For example, management accounts often include analysis of:- Employees (number, costs, productivity etc. )- Sales volumes (units sold etc. )-  Customer transactions (e. g. number of calls received into a call centre)| By definition, financial accounts present a historic perspective on the financial performance of the business| Management accounts largely focus on analysing historical performance. However, they also usually include some forward-looking elements e. g. a sales budget; cash-flow forecast. | Financial Accounting| Managerial Accounting| * Reports to those outside the organization owners, lenders, tax authorities and  regulators. | * Reports to those inside the organization for planning, directing and motivating, controlling and  performance evaluation. | * Emphasis is on summaries of financial consequences of past activities. | * Emphasis is on decisions affecting the future. | * Objectivity and verifiability of data are emphasized. * Relevance of items relating to decision making is emphasized. | * Precision of information is required. | * Timeliness of information is required. | * Only summarized data for the entire organization is prepared. | * Detailed segment reports about departments, products, customers, and employees are prepared. | * Must follow  Generally Accepted Accounting Principles (GAAP). | * Need not follow  Generally Accepted Accounting Pr inciples (GAAP). | * Mandatory for external reports. | * Not mandatory. |

Monday, March 9, 2020

Canery Row essays

Canery Row essays From the movie Canery Row by John Steinbeck, we are introduced to a little town in California full of different characters, such as Doc and the Seer. In the beginning and throughout most of the movie, there is very little reference that these two characters have anything in common. However, at the end of the movie, we have a different grasp on the two characters and their relationship to each other. Throughout the whole movie Doc is portrayed as a man who is always helping people, no matter who they are or what they have gotten themselves into. He is trying to further his career as a marine biologist by running experiments all of the time. He usually stays out of other peoples business, however, the rest of the people in the town are always prying into his personal life. During the movie, we can tell that there is not something right with Doc; he always seems to have something really bothering him, this is where Seer becomes a factor in the movie. The Seer is an old man who lives on the beach and does nothing all day. He is taken care of by Doc but does not know it. He thinks he gets food from the people above and is very grateful for it. Doc sometimes goes to visit with the Seer for a friendly conversation. When a girl finally pries into the past of Doc the two characters become linked. The Doc and the Seer used to play professional baseball and the Doc had been, at one time, a great pitcher. Then during one game, he threw a wild pitch and hit the Seer right in the head and it nearly killed him. Now the Seer lives in Canery Row where Doc takes care of him. In a way we could say that these two characters have been disenfranchised, meaning the act of withdrawing certification. When the Seer got hit in the head by the baseball, he lost everything; you could say he had his life taken away from him. When that baseball hit the Seers head, the Doc lost his fu ...

Friday, February 21, 2020

H306 Mens Health Interview Essay Example | Topics and Well Written Essays - 750 words

H306 Mens Health Interview - Essay Example Unlike in the past when I would run my garage efficiently, I currently had to leave some of my responsibilities to my juniors a feature that has drastically reduced my earnings. Patient: Prior to the discovery of the condition, I had a health cover with a local insurance company in the city. However, the insurance catered only for the time I remained admitted in hospital. Once I was discharged, I had to pay for my subsequent visits to the hospital besides the fact that I have to buy the drugs that I use in managing the condition. The costs of drugs and regular visits to the hospitals have been unbearable for my family. As I had said, I had to relinquish some of the duties I would engage in in the past at my garage. This reduced my earnings owing to the fact that the garage is a small business. Additionally, the fact that I had to keep company at all times further complicated my lifestyle since I have to engage one of my sons. The news of my condition scared the stability of my family. On the day I collapsed, it took long for the people around me to settle on the most appropriate cause of action. I therefore nearly died at the scene. When my family eventually came to see me at the hospital, my condition broke their hearts. However, they have stayed supportive always understanding my situation and sparing money whenever possible. They have reduced their demand thereby making it easier for me to cope with my condition. Despite their support and understanding attitude, I still notice the pain n their eyes and the strain they undergo having to readjust their budgets in order to sustain me. Interviewer: Sorry for the pain sir, your condition is a result of lifestyle complications. What was your lifestyle prior to the diseases and how has this changed once you realized you have the disease? Patient: My doctors told me so too and I have in deed restructured my life in order to lengthen my life and manage the condition. I loved sugary foodstuff

Wednesday, February 5, 2020

As portrayed by Virgil, what was the basis of Roman success as an Essay

As portrayed by Virgil, what was the basis of Roman success as an imperial power - Essay Example This imperialism brought about extremes of wealth and poverty that widened the social and economic gap that existed in the state (Steele). The slaves that had been acquired during the warfare helped a great deal in transforming the country side as they provided manpower that made small farms to give way to large plantations. They worked in the plantations thus resulting to the agricultural improvements that resulted in the state. This consequently made the landless crofters to move to Rome and the neighboring cities (Steele). The nobles were noted to struggle for personal domination instead of honoring the collective rule. This wealth was further viewed as having corrupted the once noble leaders. Virgil then concluded that farming was the basis of Roman success as an imperial power. This is so because the territorial conquest had permitted land use reforms that results in agricultural surplus. This improved the overall economies throughout the province and across the provincial borders. At that time, their economic growth was greater than most of other economies before industrialization

Tuesday, January 28, 2020

Impact of Divorce on Children | Essay

Impact of Divorce on Children | Essay The increase in the rate of divorce may be the most dramatic change in family life and divorce is being more and more common in the modern society. Demographers suggest that about 50% of first marriages would be voluntarily dissolved in recent years (Cherlin, 1992). Compared with statistics in the middle of 19th century which only 5% of first marriages ended in divorce (Preston McDonald, 1979), the number is shocking. Moreover, slightly more than half of all divorces involve children and adolescences aged below 18. More than one million children experience parental divorce every year (U.S. Bureau of the Census, 1998, Table 160), and Bumpass (1990) suggested that about 40% of all children will experience parental divorce before reaching adulthood. The statistics and experts opinions demonstrate the trend of increasing divorce rate, and thus there are more and more children experiencing parental divorce. In response to this, the essay is going to focus on the impact of parental divorc e in different aspects if the event happens at the time when the children are in their adolescence and young adulthood. After that, the essay will discuss the impact on them when they grow up into young adults. With the increasing rate of divorce, parental divorce happening at the time when children are in their adolescence and young adulthood is more commonplace. The parental divorce may affect the children in different aspects. The impact may also be widespread. A 25-year study of 60 post-divorce families with 131 children was conducted by psychologist Judith Wallerstein. Wallerstein (2001) finds out that the immediate effects of divorce on children may be different according to their gender, age and developmental stage. For adolescents which are one of the focuses of this essay, they will suffer depression. They will also have suicidal thoughts and express anxiety about having successful marriages. Sandford(2008) also suggests that some findings in 1990s indicated that children of divorce have lower academic achievement. They may also have some behavioral, psychological, relationship or even health problems. Researches done over the past years have consistently shown that divorce has a negative impact on the academic achievement of children of divorce. (Wallerstein, Corbin, Lewis, 1988; Popenoe, 1993). They are more likely to have low grades and score lower on academic tests. They also have lower educational aspirations and are two to three times more likely to be dropped out of school. The impact may continue to their adulthood and lower their social competence as they just achieve lower levels of education and thus lower occupational status. Thus, their income is usually less. Adolescents experiencing parental divorce may also have different psychological problems. According to Wallerstein (2001), the level of depression and anxiety is higher in children of divorce. Their self esteem is also lower and they experience more often use of psychological services. It is found that girls from divorced families are much more depressed than girls from intact families in some cases. For boys, they are more hopeless and discouraged when there are more family distresses. It should be noted that some differences in psychological well-being may due to financial disadvantages. Compared with peers from married families, children of divorce may have a lower standard of living. It is due to two reasons. Firstly, living standard of women usually decline more than mens after divorce (Ross, 1995). Secondly, most children live with their mothers after divorce (Smyth, Sheenhan and Felberg, 2001). Thus they usually live with a lower family income. They will probably move to new r esidences and to poor neighborhoods. Because of the difficult economic conditions, they would have another form of loss and become more depress. Children of divorce are also prone to different behavioral problems. They may have disorders in conduct, difficulty with authorities and behaviors that are antisocial (Hetherington and Kelly, 2002). Compared with children from intact families, they are also two to three times more probably to engage in adolescent delinquency and the conduct problems are more common among boys than in girls. Jeynes (2001) also suggests that adolescent from divorced families have alcohol more often and in larger quantities. They are also more likely to take drugs, have pre-marital sex, end up in prison and commit murder, etc. Apart from psychological and behavioral problems, relationship problems are common among children from divorced families. Sandford (2008) suggests that female adolescents that have experienced parental divorce are more likely to have earlier sexual activities and have more sexual partners than those without experience in parental divorce during their high school years. He also points out that they begin their menstruation earlier. And it seems to be some relationships between early menstruation and early sexual intercourse. It is suggested that the girls having earlier sexual activity have poor self-regulatory skills. It might be attributed to the avoidance of teaching the skills needed to gain self-control in divorced families. Moreover, it might be due to disengagement between these children and their parents at a younger age. Thus their relationship is not as good as that in intact family. Divorced childrens relationship with parents is also weaker (Sandford, 2008). According to research done by Hetherington and Kelly (2002), similar proportion of children from divorced families and from intact families feel close to their mothers (70% vs. 80%). However, only less than one-third of children report such closeness with their father while 70% of children with married parents report these feelings. The findings coincide with other researches that there are high proportion of disengaged or totally absent fathers following divorces. It is the conflicts between the ex-spouses and custody arrangements that cause fathers to feel disengaged from their children. Avoidance of child support payments is also a reason for the fathers to stay away from their children. Because of the above reasons, adolescents from divorced families view their father to be less caring. Marital instability is also another relationship faced by children from divorced families when they grow up and it wil l be discussed later in the essay. Although research found quite a lot of negative impacts on adolescents when they face parental divorce, positive consequences are also possible. A study by Arditti (1999) suggests that the children from divorced families, especially daughters, develop very close relationships with their custodial mother. It may be due to the extra care given by the custodial mothers as their fathers are disengaged from the families. The impact of divorce on children may not be short term. It is possible that divorce will affect the children in different aspects even when they grow up into young adults. Several impacts are confirmed by Amato (2000) that they are consistent with prior research. Firstly, children with divorced parents are more likely to experience psychological problems in adulthood. Secondly, they have more problems in forming and maintaining stable intimate relationships with their partners. Thirdly, they have weaker ties to their parents when they grow up into young adults.   Amato (2000) suggests that divorce is undoubtedly â€Å"a risk factor for psychological problems during childhood and into adulthood†. It is agreed that there is a tendency of adults having parental divorce experience less satisfaction with their lives, higher rates of depression and lower self-esteem. Wallerstein, Lewis and Blakeslee (2001) findings also point out that about one third of the children had serious psychological problems such as clinical depression, poor performance in school or difficulty in maintaining friendships. Moreover, their 25-year in depth study also suggests that even 25 years after the divorce, the children (now adults) â€Å"still recalled the shock, unhappiness, loneliness, bewilderment and anger†. Higher level of depression has also been found to continue in adulthood. Both men and women report comparatively worse of psychological well-being. Although Amato (2000) argues that the adults who experienced parental divorce and are suffering fro m serious psychological problems are not as many as one third of them, the effects of divorce would probably persist into adulthood. Weaker ties to their parents is another impact when children grown up into young adults. Weisberg and Appleton (2003) describe a survey carried out by a sociologist. 1500 adults who had experienced a divorce before the age of 14 and a comparison group of children from intact family were surveyed. It was found that children of divorce (now adults) felt they were outsiders in their own home. They also had frequent feelings of being alone and were less likely to seek comfort from their parents. The weak ties to their parents usually persist into their adulthood. Another research done by Hetherington and Kelly (2002) also found that less than one-third of children of divorce report close feelings to their fathers. And even when they grow up into adult, they doubt whether their fathers care or love them. It is also suggested that children with parental divorce would have more problems in forming and maintaining stable intimate relationships with their partners (Amato, 2000). According to Hetherington and Kelly (2002), children of divorce are more likely than children of intact families to have marital instability and lower marital satisfaction. They generally have more thoughts about divorce and the divorce rates among children of divorce are also a bit higher when they grow up into adults. The phenomenon may be explained by the wariness to commit to a relationship, perceiving divorce as an alternative for unhappy marriages. Moreover, a contentious family life may result in generally weaker relationship skills. Weisberg and Appleton (2003) also stated that a lot of studies have shown that parental divorce is a risk factor for other problems in adulthood. The problems include low socioeconomic attainment, poor subjective wellbeing, increased marital problems, and a greater likelihood of seeing ones own marriages end in divorce (Amato, 1999). It might be hard to understand why the problems persist into adulthood. Weisberg and Appleton (2003) suggested that parental divorce may lead to financial crisis. The original plans to attend college may be abandoned, thus resulting in lower occupational attainment and wages throughout adulthood. For children who were exposed to poor parental models of interpersonal behavior, they might have difficulty when wanting to form stable, satisfying and intimate relationship as young adults. The above considerations suggest that it may be possible that some children show improvement soon after parental divorce in terms of behavior or relationship, however, some effects might only appear when the children reach young adulthood. Although the essay focuses on the impact of parental divorce on children, it is also important to note some of the methods that the children can adopt in order to adjust to divorce and minimize the negative impacts brought. Kelly (2003) suggests that conflicts between parents should be diminished. Competent residential parenting such as warmth and emotional support and adequate monitoring to the children is also needed. The non-residential parents also have a role. They should offer stable financial support to the divorced family. Regular contacts with the children and involvement in issues related to their children should also be carried out in order to help with childrens adjustment to divorce. It is the effort made by the parents that can minimized the impacts mentioned above. As discussed above, it is shown that parental divorce is an upsetting and disruptive event in the lives of the children. Although some scholars argue that children can develop successfully in a variety of family structures and view divorce as an escape from a dysfunctional home environment, more evidences and findings suggest that having experience of parental divorce may cause different problems such as psychological, emotional, behavioral and social problems. The children in divorced families may also deal with relationships in a disturbed manner. The effect may not be short term and can extent to adulthood in some cases. There may be intergenerational transmission of divorce and the adults may have difficulties in dealing with intimate relationship. The marriages of the adults with parental divorce experience would also be affected. It is arguable that not all children from divorced families suffer from these problems. And there are a lot of factors affect the impacts of parental divorce on children or the recovery process such as access to parents or parental support. Sex difference, the family structure or the relationship with parents may also be some of the factors. Although many factors should be considered, some negative impacts are proved that they would happen more frequently among children with parental divorce. And we should understand the impacts in order to find measures that can help the children adjust to divorce.

Monday, January 20, 2020

Fixing Racial Disparity Essay -- Racism

The term minority encompasses African Americans and Hispanics that live in the United States. These special populations are often overrepresented in the criminal justice system. Although our laws designed to make life fair and equal for minorities, they still report unfair treatment and struggles that white Americans do not experience. Policy changes in areas of social prevention, arrest and incarceration, and discharge, such as implementing help groups for youth, reform of and creating trust in law enforcement, and strong exit programs, can lead to fair treatment and reduction of representation of minorities in the criminal justice system. When looking at social prevention, one issue that should be addressed is education problems in minority communities suggested by Horton (2002). Judge Mathis speaks about young African Americans turning to crime because they are uneducated and how a mentor who pushed him to go to school made a big difference in his life (Levister, 2010). According to Charles Ogletree, a Harvard Law School Professor, after school and mentoring programs help keep young people out of trouble (Devarics, 2009). There should be policies to provide these programs to the youth. There should also be policies that provide funding to update or build new schools and ensure proper teaching methods in these communities. A recent lawsuit in Tangipahoa Parish, LA addressed this issue. It was presented as a desegregation suit but all the plaintiff wanted was equal education opportunities for the children in minority communities as are afforded children in neighboring white communities. This suit resulted in new schools, renovation of others, implementation of similar education programs, and fair access to extracurricular ac... ...al Profiling: What the Evidence Suggests. Journal of Human Behavior in the Social Environment, 6(4), 87. Retrieved from EBSCOhost. Jan, T. (2009, July 20). Harvard professor Gates arrested at Cambridge home. Retrieved May 27, 2012, from boston.com website: http://www.boston.com/news/local/breaking_news/2009/07/harvard.html Levister, C. (2010, March 4). Judge Mathis reaches out with 'jail to judge' message. Retrieved May 27, 2012, from blackvoicenews.com website: http://www.blackvoicenews.com/news/44093-judge-mathis-reaches-out-with-jail-to- judge-message.html Toth, R. C., Crews, G. A., & Burton, C. E. (2008). In the margins: Special populations and American justice. Upper Saddle River, NJ: Pearson Prentice Hall Walker, S., Spohn, C., & Delone, M. (2012). The color of justice race, ethnicity, and crime in America (5th ed.). Belmont, CA: Wadsworth.

Sunday, January 12, 2020

Lipid Profiles In Postmenopausal Women Health And Social Care Essay

Aim: Aromatase inhibitors are presently used in accessory to the former gold criterion Tamoxifen or as first line hormone therapy in postmenopausal adult females with chest malignant neoplastic disease. Suppressing the aromatase mechanism of action impedes the synthesis of estrogen, forestalling estrogen protection on lipid profiles. This literature reappraisal examines, discusses, and analyzes peer-reviewed published clinical tests analyzing the effects of anastrozole, exemestane, and letrozole, on lipid profiles in postmenopausal adult females with estrogen dependent chest malignant neoplastic disease. Decisions: Overall, there are minimum, if any, unfavourable effects of aromatase inhibitors on lipid profiles. However, restrictions of little population sizes, fluctuations in design methods, and old Tamoxifen usage, make it hard to accurately assess hazard. Long term prospective surveies utilizing big sample sizes and patients with no exposure to any other hormone intervention besides aromatase inhibitors, are needed to accurately measure if inauspicious effects on lipid profiles exist from the utilizing aromatase inhibitors. Healthcare professionals should go on to supervise lipoids in postmenopausal adult females with chest malignant neoplastic disease and develop individualized intervention programs utilizing current recommendations. Cardinal Wordss: aromatase inhibitor, chest malignant neoplastic disease, post-maturity, lipid, Anastrozole, Letrozole, Exemestane, cholesterin, and lipid metamorphosis. Aromatase Inhibitors Risk of Adverse Effects on Lipid Profiles in Postmenopausal Women with Breast Cancer: A Literature Review Introduction Breast malignant neoplastic disease pestilences about 2.5 million adult females in the United States, 1 doing it one of most prevailing signifiers of tumor that healthcare practicians dainty today. The hazard of developing chest malignant neoplastic disease increases with age, with one in 13 postmenopausal adult females developing the disease.2 Nearly 70 per centum of those postmenopausal adult females will hold a endocrine dependant ( estrogen positive ( ER+ ) , progesterone positive ( PR+ ) ) signifier of chest malignant neoplastic disease that utilizes estrogen as its chief alimentary beginning for the proliferation of the tumour. 2, 3, 4 In postmenopausal adult females, estrogen is chiefly synthesized in the peripheral tissues, chest, musculus, adipose, tegument by the enzyme aromatase.4,5 Aromatase converts adrenal androgens into estrogen via the CYP450 enzyme pathway.4, 5, 6, Suppressing aromatase and hindering this transition limits the sum of estrogen available for use by tum our cells, later forestalling growing and spread. Through this mechanism of action, steroidal ( Exemestane ) and non-steroidal ( anastrozole and letrozole ) aromatase inhibitors have shown to be extremely efficacious in the intervention of ER+/PR+ chest malignant neoplastic disease in postmenopausal adult females compared to that of Tamoxifen.5 Multiple landmark surveies ( MA.17, 2 ATAC, 7 BIG 1-98, 8 and EORTC9 ) , suggest that Tamoxifen is no longer a gilded criterion, and now recommend utilizing AIs as first line hormone therapy in these patients.5 With the spread outing usage of AIs by practicians in the intervention of endocrine dependent chest malignant neoplastic disease and the subsequent betterment in disease free endurance rates, more postmenopausal adult females are populating long plenty to see other comorbidities, such as cardiovascular disease ( CVD ) .4 Since CVD is the primary cause of mortality in postmenopausal adult females, 10 understanding the associated inauspicious effects AIs pose on cardiovascular hazard factors is pertinent. Lipid biomarkers are often assessed clinically to find a patients hazard of developing CVD. Previous epidemiologic surveies have shown that estrogen is protective and good to some cardiovascular hazard factors, specifically lipid profiles, via its direct effects on the endothelial cells found in blood vessels.6,11 Estrogen alters concentrations of lipoids in the blood ; diminishing serum concentrations of entire cholesterin ( TC ) , low-density lipoprotein ( LDL ) , and triglycerides ( TRG ) , while increasing serum concentrations of high-density lipoprotein ( HDL ) .11, 12 Therefore, it is thought that postmenopausal adult females taking AIs are deprived of this cardioprotective consequence of estrogen since its synthesis is being prevented by suppressing the aromatase transition mechanism. Therefore, the inquiry can be proposed: Make aromatase inhibitors adversely affect lipid profiles and later present an increased hazard of developing cardiovascular disease in postmenopausal adult females with ER+/PR+ chest malignant neoplastic disease? This literature reappraisal of current clinical test informations examines and assesses the usage of AIs, Exemestane ( Aromasin ) , Anastrozole ( Arimidex ) , and Letrozole ( Femara ) , on the inauspicious effects of the lipid profiles of postmenopausal adult females with ER+/PR+ chest malignant neoplastic disease. Search footings included cardiovascular, aromatase inhibitor, chest malignant neoplastic disease, post-maturity, lipid, Anastrozole, Letrozole, Exemestane, plasma lipoid, cholesterin, and lipid metamorphosis. MEDLINE in Pubmed, MEDLINE ( on EBSCO ) , and OVID were used to seek for peer-reviewed diary articles published between the old ages 2005 to 2010. Recent grounds showing the effects AIs render on the lipid profiles of postmenopausal adult females with estrogen dependent chest malignant neoplastic disease is discussed, analyzed, and reviewed in the undermentioned subdivisions. AROMATASE INHIBITORS EFFECT ON LIPID PARAMETERS Depriving chest malignant neoplastic disease stricken postmenopausal adult females of the benefit of estrogen via the AI mechanism is thought to hold damaging effects on CVD hazard factors. Several clinical tests utilizing assorted design methods have been conducted and show variable effects of AIs on the different cholesterin parametric quantities and lipoproteins. Table 1 summarizes the effects of AIs on assorted lipid biomarkers in the postmenopausal adult female with ER+/PR+ chest malignant neoplastic disease, and all surveies in the tabular array are discussed in the following subdivisions. Placebo Controlled Tests Two surveies have evaluated the consequence of AIs versus placebo on lipid biomarkers. As a secondary end point, Cigler et al13 studied the effects of Letrozole versus placebo on serum lipid parametric quantities ( TC, HDL, LDL, TRG ) in 60 seven postmenopausal adult females utilizing a random, placebo-controlled design. Lipids were measured at baseline and during the 3rd, 6th, 12th, and 24th months, and the per centum alteration from baseline was calculated for each month. Researchers noted a statistically important lessening in the TC at month 3 ( P value=0.052 ) in the Letrozole arm of the survey. The other parametric quantities ( TRG, LDL, and HDL ) measured were non significantly changed from baseline in either the Letrozole or the placebo weaponries. Writers concluded that Letrozole modestly decreases TC at 3 months ; nevertheless, the consequence is non sustained throughout the intervention clip period.13 The cogency of consequences in the lipid part of this survey are questio nable because of the imbalanced figure of participants in each intervention group, and the little population size that remained at the terminal of the 24 months ( Letrozole: 26 patients, and placebo: 16 patients ) . It is hard to measure accurate tendencies in informations with little population sizes, and consequences should be verified utilizing similar survey methods with larger population sample sizes. A confusing variable in this survey was the old usage of Tamoxifen in some patients and non others. Tamoxifen has shown to hold good effects on lipoids ; 14, 15 therefore, the consequences from patients that had antecedently taken Tamoxifen may non be a true representation of the effects of the AI entirely on lipid profiles. Another placebo controlled test utilizing different design methods was conducted by Lonning et al16 and contrasting consequences were found. The effects of Exemestane versus that of placebo on plasma lipoids in postmenopausal adult females with resectable chest malignant neoplastic disease was studied by Lonning et al.16 In a dual blind manner, one hundred 40 seven patients were indiscriminately assigned to an Exemestane intervention group or a placebo intervention group. Measurements of lipid biomarkers ( TC, HDL, LDL, TRG, ApoLipoprotein A1, lipoprotein A, ApoLipoprotein B, homocysteine ) were taken at baseline, and at the 3rd, 6th, 12th, and 24th month. Results revealed that the Exemestane intervention group had a statistically important ( P value & A ; lt ; 0.001 ) lessening in HDL versus that of the placebo intervention group. Besides, a statistically important ( p=0.004 ) lessening in Apolipoprotein A1 occurred in the Exemestane intervention group versus that of the placebo intervention group. Writers concluded that the steroidal AI, exemestane has modest effects on HDL lipid biomarkers and those hazard factors for CVD should be followed overtime.16 This survey included more participants than Ciglers study ; hence, the consequences seen here may hold more cogency. Besides, a different AI was used in each test, and this variable could account for the disagreement in consequences between the two surveies. No old Tamoxifen usage was denoted in the survey by Lonning et Al ; 16 therefore, the consequences are a better representation of the effects of the AI on lipoids without confusing influences of Tamoxifen. More placebo controlled tests are necessary to to the full understand the effects of AI on lipoids in postmenopausal adult females with endocrine dependent chest malignant neoplastic disease, and to denote if a true lessening in HDL exists. The following subdivision discusses tests in which AIs were compared with Tamoxifen alternatively of a placebo as the intercession intervention groups to be assessed. Tamoxifen Comparative Tests Surveies have been conducted utilizing Tamoxifen as a comparative intervention group to that of Exemestane, and their several inauspicious effects on lipid profile alterations are discussed. The TEAM Greek bomber study17 randomized postmenopausal adult females with early chest malignant neoplastic disease into an Exemestane arm ( 77 patients ) or into a Tamoxifen arm ( 65 patients ) , and evaluated HDL, LDL, TRG, and TC at baseline, and at 12, 18, and 24 months. Results indicate that TC decreased overtime in both intervention groups ; nevertheless, those in the Tamoxifen arm had a crisp diminution at month 18 and 24, doing the difference between groups at that clip period statistically important with P value=0.020 and P value=0.0087, severally. Both interventions had a statistically important lessening in HDL ; nevertheless, the Tamoxifen group maintained higher degrees of HDL, leting for a more favourable consequence than exemestane, with a statistically important average difference ( P=0.011 ) between the intervention groups. The Tamoxifen intervention group had a important consequence on the LDL parametric quantity doing a steep lessening in values overtime. exemestane had failed to demo any important alteration on LDL. The TRG parametric quantity revealed no noticeable tendencies for either intervention regimen. Research workers concluded that Tamoxifen has a favourable consequence on TC and LDL, while Exemestane has a more indistinct consequence on lipid biomarkers.17 The lessening in HDL in this survey is in harmony with that of Lonning et al.16 One restriction is that all four lipid parametric quantities were non accounted for in all patients in each intervention group ; hence, tendencies seen in each parametric quantity may non stand for the true tendency that would be present if all values were recorded for all patients at all measurement clip periods. This survey reiterates the idea that Tamoxifen has good effects on lipoids ; accordingly, it is hard to accurately measure the hazard of AI when the comparative intervention group is Tamoxifen. 14 Though some restrictions were present in this survey, comparative consequences were seen by Francini et al14 in another test utilizing different methods than the TEAM Greek bomber survey. Francini et al14 conducted a survey in which 55 postmenopausal adult females who had antecedently been treated with no less than 2 old ages of Tamoxifen were randomized into two intervention groups: either continue Tamoxifen or exchange from Tamoxifen to Exemestane. Lipid parametric quantities were measured at baseline and at 6 and 12 months. Consequences yielded were statistically important in the Exemestane arm of the survey entirely demoing a lessening in HDL overtime ( p value & A ; lt ; 0.05 ) , an addition in LDL overtime ( p value & A ; lt ; 0.01 ) , and a lessening in TRG overtime ( P value & A ; lt ; 0.01 ) . The differences between the Tamoxifen and Exemestane intervention group were non important except for the LDL biomarker ( p value & A ; lt ; 0.05 ) . Writers concluded that the addition in LDL of the Exemestane group may be due in portion to participants being antecedently treated with Tamoxifen, which is known to hold good effects on LDL.14 Francinis survey and the TEA M Greek bomber study17 indicate that there was a lessening in the HDL parametric quantity in the Exemestane intervention group versus that of the Tamoxifen intervention group, proposing that AIs may hold an inauspicious consequence on HDL degrees. This lessening in HDL was besides noted in the ATENA trial18 in which Tamoxifen had been antecedently used for 5-7 old ages before the patients were assigned to have either Exemestane or no intervention, merely observation. The addition in LDL found in the survey by Francini14 was besides seen in the ATENA test ; 18 nevertheless, the TEAM Greek bomber study17 did non back up this determination. It must be kept in head that patients in the survey by Francini14 and the ATENA trial18 had antecedently been treated with Tamoxifen before get downing intervention with AIs, while patients in the TEAM Greek bomber study17 were non. Hence, the design differences could account for the fluctuation of consequences between surveies on the LDL, TRG, and TC parametric quantities. A likewise designed survey by Montagnani et al15 exposed comparable consequences to the survey by Francini. Montagnani et al15 investigated the effects of Exemestane after anterior intervention with Tamoxifen, and indiscriminately assigned 60 eight postmenopausal adult females to go on taking Tamoxifen ( 20 milligrams daily ) or exchange to the aromatase inhibitor, Exemestane ( 25 milligrams daily ) for 2 old ages. Parameters ( TC, HDL, LDL, TRG ) were measured at baseline and at 12 and 24 months. Consequences showed that the Exemestane intercession had a important lessening in HDL, while the Tamoxifen group showed no significance in alteration from baseline. Therefore, a important difference between the intercession groups ( p value & A ; lt ; 0.05 ) was noted. Besides in the Exemestane group, LDL was increased from baseline ; nevertheless, no alteration was seen in the Tamoxifen group. The between group differences were besides statistically important with a P value & A ; lt ; 0.05. The Exemestane group besides had a statistically important lessening in TRG doing the between group differ ences important with a p value of & A ; lt ; 0.05. The consequences found in this survey showed some similarities with those discovered by Francini et al.14 Montagnani revealed important differences between groups for HDL, LDL, and TRG parametric quantities, while Francinis survey merely showed important differences between groups for LDL. In both surveies, the aromatase inhibitor was compared with go oning Tamoxifen after the patients had already used Tamoxifen, hence some of the consequences may hold occurred from taking the good effects of Tamoxifen instead than uncovering damaging effects of the AI. Both Francini and Montagnani revealed lessenings in TRG in the Exemestane arm. This would be considered a favourable consequence of utilizing AI, but since Tamoxifen negatively affects TRG and Tamoxifen was antecedently used by the Exemestane patients, the simple remotion of the unfavourable consequence of Tamoxifen could account for the consequence. To increase the respectability of these findings, comparable consequences should be confirmed in likewise designed surveies utilizing larger sample population sizes without old exposure to Tamoxifen. Banerjee et al19 designed yet another survey comparing a different AI, Anastrozole, to Tamoxifen, and to a combination of Anastrozole with Tamoxifen. The IMPACT trial19 compares the effects of utilizing Anastrozole, Tamoxifen, or a combination of Anastrozole/Tamoxifen on the lipid profiles of postmenopausal adult females with chest malignant neoplastic disease. In a stage III, randomized, double-blind multicentre trial,19 three hundred 30 patients were assigned to have either Anastrozole ( 1 milligrams daily ) + Tamoxifen placebo, Tamoxifen ( 20 milligrams daily ) + Anastrozole placebo, or a combination of both ( Tamoxifen 20 mg day-to-day + Anastrozole 1mg daily ) for a period of 12 hebdomads. Measurements for TC and HDL were taken at baseline and three months. Results revealed that the Tamoxifen merely intervention group had a statistically important lessening in the TC lipid parametric quantity ( p value & A ; lt ; 0.05 ) , while the Anastrozole merely intervention group had an addition in TC lipid parametric quantity that was non statistically important ; nevertheless, the difference between the two groups was important. The c ombination group consequences showed a important lessening in TC ( P value & A ; lt ; 0.05 ) , nevertheless the between groups differences were non important. A statistically important addition in HDL from baseline was noted overtime in all intervention groups ( P & A ; lt ; 0.05 ) , nevertheless the difference between the groups was non important. Writers suggest that, although there was a little addition in TC in the Anastrozole merely group, this negative consequence was counterbalanced with the positive consequence of the addition of HDL in the Anastrozole group, and that there is no damaging consequence on the lipid profile when utilizing the AI, Anastrozole.19 Measurements were merely taken over a 3 month clip period, therefore consequences are limited and the effects seen may non prolong through longer intervention tests. This addition in HDL in the AI intervention group is contrary to the consequences seen in antecedently discussed surveies. Different AIs were used in each t est and this unsimilarity in methods could account for the differences. Studies reexamining the disparities between AIs are necessary to find their several effects on lipid profiles and to measure if an AI is more good or damaging than the others. Comparison between Aromatase Inhibitors It is of import to understand the differences between each aromatase inhibitors several effects on lipid profiles to assist healthcare practicians choose the appropriate drug regimen for each single patient. In a multi-centre, unfastened, randomized survey, McCloskey et al5 compared the effects of Anastrozole, Letrozole, and Exemestane on lipid profiles in one hundred and two postmenopausal adult females, and randomized them into one of three intervention groups: Anastrozole ( 1 milligrams daily ) , Letrozole ( 2.5 milligrams daily ) , or Exemestane ( 25 milligrams daily ) , for 24 hebdomads with a 12 hebdomad follow up period. Measurements of lipid biomarkers ( TC, TRG, LDL, HDL, LDL/HDL ratio, Apolipoprotein B/Apolipoprotein A-1 ratio ) were taken at baseline and at the 12th, 24th, and 36th hebdomad. Consequences revealed that Exemestane had a important lessening from baseline in TC, nevertheless the differences between the three intervention groups were non statistically important ( p value=0.535 ) . The LDL/HDL ratio parametric quantity was significantly different for all three groups at the 12th and 24th hebdomad measuring, with Exemestane giving the greatest alteration ( p=0.007 ) compared to Letrozole ( p=0.025 ) and Anastrozole ( p=0.045 ) . This increased ratio in the Exemestane intervention group was due to the statistically important lessening in HDL ( p value & A ; lt ; 0.001 ) . The TRG measuring for all groups showed much variableness, with Letrozole demoing a statistical important addition at 12 hebdomads ( p=0.011 ) versus the other AIs. This alteration from baseline did non last through the 24 hebdomad measurement period. No other alterations were noted between the three intervention groups. Writers suggested that those treated with Exemestane have an addition in hazard of inauspicious effects on the ratios finding atherogenesis.5 The lessening in the HDL parametric quantity in patients utilizing Exemestane is in understanding with the antecede ntly mentioned surveies that used Exemestane as an AI comparator of pick. Since Tamoxifen was non a confounding factor here, the suggestion that Exemestane perchance adversely effects HDL, now becomes a more significant and valid statement because the consequence is still seen without Tamoxifen act uponing the consequence. However, it must be considered that this survey used healthy postmenopausal adult females, non breast malignant neoplastic disease patients, as the sample population evaluated, and the consequences can non be imposed as the same consequences that might hold occurred if the population had used a sample of postmenopausal adult females with chest malignant neoplastic disease. Long clinical surveies utilizing the right population sample and sample size should be conducted to further understand the impact of each AI on the postmenopausal chest malignant neoplastic disease patient. This is one of the lone surveies available measuring the inauspicious effects of each par ticular AI compared to one another. More surveies are necessary to corroborate the consequence that Exemestane offers more inauspicious hazard compared to Letrozole and Anastrozole. Decision Tamoxifen has been in usage for more than 30 old ages, and was considered the gilded criterion hormone therapy for handling postmenopausal adult females with endocrine dependent chest cancer.15, 20 Large epidemiologic surveies have shown that AIs are more efficacious than Tamoxifen in overall and disease free endurance rates, and hence are now recommended as first line accessory hormone therapy for postmenopausal adult females with chest cancer.3,15 With their known mechanism of action of striping postmenopausal adult females of serum estrogens, therefore taking estrogens protective effects on these cardiovascular hazard factors,6, 11 there is concern that AIs may hold inauspicious effects on lipid profiles. Most writers concluded that aromatase inhibitors have minimum effects or no inauspicious effects on lipid profiles in postmenopausal adult females with chest malignant neoplastic disease. However, it is hard to measure the true consequence of AIs on lipid profiles with Tamoxifen as the comparator since it has proved benefit on some lipid parameters,14 and because of the many different design methods used. Small sample sizes were restrictions in a few surveies ; therefore, the tendencies yielded in those tests may non be genuinely declarative of postmenopausal adult females with chest malignant neoplastic disease. Long term prospective surveies utilizing big sample sizes and patients with no exposure to any other hormone intervention besides AI, are needed to accurately measure if inauspicious effects on lipid profiles exist from the usage of AIs. From the current available information, though minimally, HDL is the parametric quantity most adversely affected by the usage of AI. This may be a cause of concern for some practicians since lessenings in go arounding sums of HDL are linked with additions in cardiovascular disease.15 Since HDL is considered good cholesterin and a positive hazard factor, diminishing the sum available in blood could perchance hold damaging effects on CVD. Healthcare practicians should be cognizant of this possible hazard of diminishing HDL with AI usage so that proper monitoring in their patients may be performed. Given that a current intervention option still includes the usage of Tamoxifen followed by exchanging to an AI, it is particularly of import to supervise lip id profiles since some studies14, 15, 17 have shown unfavourable effects on lipid profiles when doing this switch. To find if an existent hurt on CVD hazard factors occurs in adult females taking the non steroidal and steroidal aromatase inhibitors, more long term clinical tests should be conducted. In decision, aromatase inhibitors are being used more and more as first line accessory intervention in postmenopausal adult females with chest malignant neoplastic disease. Though it depletes estrogen beginnings, surveies show no well damaging effects on lipid profiles, with most merely demoing minimum, if any, inauspicious consequence. Placebo controlled surveies utilizing equal patient populations and sample sizes for appropriate sums of clip, are necessary to accurately depict the hazards of AIs on cardiovascular hazard factors. Healthcare practicians should go on to supervise lipid profiles in postmenopausal adult females with chest malignant neoplastic disease and develop individualized intervention programs utilizing current recommendations. Specific safety steps for patients utilizing AIs are non necessary,16 and the effects seen in the surveies mentioned in this reappraisal suggest that long term monitoring of all lipid parametric quantities should be a portion of the postmen opausal adult female with chest malignant neoplastic diseases intervention program. Surveillance of hazard factors overtime in these adult females with should assist forestall unfavourable cardiac events.